PROGRAM
16 Invited speakers + 31 Talks selected from the submitted abstracts
Wednesday, July 1st (Duclaux amphitheater)
8:15 Registration with refreshments
8:50 – 10EWLM Welcome address by Gerard Bannenberg and Xavier Norel
Educational SESSION: Control at the Source in Lipid Biology
9:00 – Opening address by chairpersons: Valérie Urbach and Per-Johan Jakobsson
9:05 - 9:30 – Thierry Durand -
1IBMM, CNRS, France (25 min)
How to analyse NEO-PUFAs and Natural Lipophenols: Thanks to LC-MS/MS and Targeted Lipidomics
9:30 - 9:55 - Beatrix Suess -
Technical University of Darmstadt, Germany (25 min)
RNA-based control at the site of signal generation
9:55 - 10:20 - Dieter Steinhilber - Goethe University Frankfurt, Germany (25 min)
MicroRNA regulation at the origin of lipid mediator synthesis
COFFEE BREAK (Modules, and Sponsor stands visit) 10:20 - 10h45
1st Sponsored SESSION: Lipid mediator analytics and biomarkers
10:45 - Welcome by chairpersons: Gijs Kooij and Marc Dubourdeau
10:50 – 11:15 - Laura Bindila* - Medical University Mainz, Germany (25 min)
4D Lipidomics for cellular and circulatory phenotyping with diseases
11:15 – 11:40 - Ingela Lanekoff* - Uppsala University, Sweden (25 min)
Mapping the distribution of lipid mediators in tissue
11:40 – 12:40 - Selected speakers (3x 20 min incl Q&A)
Negar Mir - University of Toronto, Canada
Species-Level Biomarkers of MASLD and MASH Progression in Normolipidemic Individuals with Obesity
Serhii Chornyi - Vrije Universiteit Amsterdam & Leiden University Medical Centre, The Netherlands
Profile and origin of lipid mediators in pneumococcal meningitis
Marta Reina-Couto - Univerity of Porto, Portugal
Multimarker profiling of inflammatory and resolution mediators to differentiate septic from cardiogenic shocks
LUNCH BREAK 12:40 - 14:25 (Modules, and Sponsor stands visit)
2nd Sponsored SESSION: Analytical challenges and clinical applications of oxylipins
The Lipidomics Research and Study Group (GERLI)
14:25 - Welcome by chairpersons: Cécile Gladine and Thierry Durand
14.30 – 14.55 - Denise Biagini* - University of Pisa, Italy (25 min)
Unlocking oxylipin and PUFA profiling in unconventional biofluids:
Challenges, pitfalls, and clinical potential
14.55 – 15.20 - Craig Wheelock*- Karolinska Institutet, Stockholm, Sweden (25 min)
Targeted Spatial Metabolomics for Mapping Lipid Mediator-Related Inflammation in the Lung
15:20 – 16:20 - Selected speakers (3 x 20 min incl Q&A)
Jean-Marie Galano - IBMM Montpelier, France
Trioxilins Are Back: Rediscovering Overlooked Oxylipin Chemistry
Carlos R. Canez - University of Alberta, Canada
When Contaminants Masquerade as Lipids: Building a Contaminant Library to Prevent Misannotations in Lipidomics
Jose Luis Moreno-Casillas - Health Research Institute La Fe (IIS La Fe), Valencia, Spain
Comparative evaluation of microsampling devices for oxylipin analysis in newborn blood
(+10 min) Award ceremony "GREMI Thesis Prize - Michel CHIGNARD"
Laureate 2025: Alberto IANNUZZO
18:00 OPENING RECEPTION (CIS Building)
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Thursday, July 2nd (CIS Building)
8:00 Registration with refreshments
8:50 – Welcome address by Gerard Bannenberg & Xavier Norel
9:00 - 9:40 Opening Plenary Lecture, chair person: Xavier Norel
Nan Chiang*- Brigham and Women's Hospital and Harvard Medical School, Boston, USA
Specialized Pro-resolving Mediator Pathways and Receptors In Orchestrating Resolution and Regeneration.
COFFEE BREAK (+ poster viewing, and Sponsor stands visit, CIS Building) 9:40 - 10:40
SESSION 1: Lipid mediators in Infection, inflammation and immunity 10:40 -12:15
10:40 - Welcome by chairpersons: Valérie Urbach & Adriano Rossi
10:45 - 11:10 Julia Esser-von Bieren* - University of Lausanne, Switzerland
Role of macrophage-derived prostanoids in helminth infection
11:10 – 11:35 Martin Giera* - Leiden University Medical Center, Leiden, Netherlands
Lipid Mediator, Not Lipid Mediator:
Redefining Bioactive Lipids Beyond Oxylipins
11:35 – 12.14 Selected speakers (3x13 min incl Q&A)
11:35 – 11.48 Jerome Hendriks - Univeristy of Hasselt, Belgium
Loss of CD36 induces disease-associated OPCs in the brain via pro-inflammatory eicosanoid signaling impairing remyelination
11:48 – 12.01 Stephania Libreros - Yale School of Medicine, USA
Cracking the Lipid Mediator Code of Septic Neutrophils
12:01 – 12.14 Helena Fisk - University of Southampton, UK
EPA+DHA and their monohydroxy-oxylipin metabolites increase mitochondrial respiration capacity in M0 but not M1 macrophages
LUNCH BREAK 12:15 - 13:45 (CIS Building)
SESSION 2: Lipid mediator chemistry and molecular biology 13:45 -15:10
Welcome by chairpersons: Gijs Kooij & Chengcan Yao
13:50 - 14:15 - Derek J. Taylor* - Case Western Reserve University, Cleveland, USA
Structures of inhibitor-bound 15-PGDH:
insights into molecular mechanisms and regenerative therapeutic opportunities
14:15 - 14:40 - Jesmond Dalli* - William Harvey Research Institute - Queen Mary University of London, UK
Decoding resolution biology:
New insights into molecular dysregulation driving disease progression
14:40 – 15.06 Selected speakers (2x13 min incl Q&A)
14:40 – 14.53 Robert Hofstetter - University Jena, Germany
Functional lipid mediator screening identifies prostaglandin D2 as suppressor of mPGES-1 expression via the Keap1-Nrf2 axis in macrophages
14:53 – 15.06 Christoph Matti - University College London, UK
Novel LysoPS GPCR Signalling in B Cell Responses
COFFEE BREAK (+ poster viewing, and Sponsor stands visit, CIS Building) 15:10 - 16:10
YOUNG INVESTIGATOR SESSION 16:10 - 17:30
Chair persons: Mireille Alhouayek & Gerard Bannenberg
10 Talks selected from the submitted abstracts
(6 + 2 min Q&A each, timed)
SHORT BREAK (10-15 min)
SESSION 3: Lipid mediators in cancer biology 17:45 - 19:10
Welcome by chairpersons: Cristina López-Vicario & Per-Johan Jakobsson
17:50 - 18:15 - Paola Patrignani* - G. d'Annunzio" University Medical School, Chieti, Italy
The crucial role of platelet eicosanoids in cancer:
An opportunity to
prevent cancer development and metastasis
through targeted therapeutic
interventions
18:15 – 18.40 - Anna Martling*- Karolinska Institutet & University Hospital, Stockholm, Sweden
Low-Dose Aspirin for Secondary Prevention in Colorectal Cancer:
Results from the Nordic ALASCCA Trial
- A 50% Reduction in Recurrence in Genetically Selected Patients
18:40 – 19:06 Selected speakers (2x13 min incl Q&A)
18:40 – 18.53 Karin Larsson - Karolinska Institutet & University Hospital, Stockholm, Sweden
Relieving Prostaglandin-Mediated Immunosuppression Unlocks Neoantigen Vaccine Efficacy
18:53 – 19.06 Emiko Yoda - Showa Medical University, Japan
Role of mPGES-1 in irinotecan-induced gastrointestinal toxicity
20:00 GALA DINNER (Cruise on Seine River)
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Friday, July 3rd (CIS Building)
8:15 Registration with refreshments
09:00 - 09:05 – Morning address by Giulio Muccioli
09:05 - 09:45 Second Plenary lecture, Chair person: Giulio Muccioli
Vincenzo Di Marzo* - ICB-CNR, Pozzuoli, Italy / Université Laval, Québec City, Canada
The endocannabinoidome, the gut microbiome and dietary fatty acids:
a well functioning triangle.
COFFEE BREAK (+ poster viewing, and Sponsor stands visit, CIS Building) 9:45 - 10:45
SESSION 4: Dietary lipids and supplements 10:45 - 12:05
Welcome by chairpersons: Chengcan Yao & Marc Dubourdeau
10:50 - 11:15 - Robert Caesar* -
University of Gothenburg, Sweden
Interaction between lipids and gut microbiota influences metabolic health
11:15 - 11:40 - Regina Rodrigo* - Principe Felipe Research Center (CIPF), Valencia, Spain
Inflammation resolution in retinal degeneration:
The emerging role of specialized pro-resolving lipid mediators in hereditary retinal diseases
11:40 – 12:06 Selected speakers (2x13 min incl Q&A)
11:40 – 11.53 Maria Jose Ruiz-Pastor - Murcia Institute of Biomedical Research (IMIB), Spain
Beyond DHA: Key Fatty Acids Driving Retinal Degeneration and Their Implications for Nutritional Therapies
11:53 – 12.06 Simin Zhang - Karolinska Institutet, Sweden
Low dose n-3 PUFA supplementation shifts plasma oxylipins from AA- to EPA-derived pathways: a sub-study of the GISSI-Prevenzione trial
LUNCH BREAK 12:06 - 13:40 (CIS Building)
3rd Sponsored SESSION on Resolution of Inflammation 13:40 - 15:10
COST EU RESOLVE
Welcome by chairpersons: Véronique Witko & Oliver Werz
13:40 – 14:20 “Introducing the COST-EU-Resolve”
Speakers: Jesmond Dalli, Cristina Lopez, Denise Biagini and Joan Clària.
(Overview, activities of WG1-6, options for young researchers, Q&A)
14:20 – 15:10 “Concepts of inflammation resolution”
Mauro Perretti* (20+5 min): Resolution of Inflammation; state-of-the-art and translational landscape
Ana Maria Briones* (20+5 min): Role of specialized proresolving mediators in cardiovascular damage in hypertension
COFFEE BREAK (+ poster viewing, and Sponsor stands visit, CIS Building) 15:10 - 15:40
SESSION 5: Lipid mediators in cardiovascular and metabolic diseases 15:40 – 17:15
Welcome by chairpersons: Xavier Norel & Giulio Muccioli
15:45 - 16:10 - Philippe Gabriel Steg* - Bichat Hospital, INSERM U1148, Paris, France
Clinical trials of omega 3 fatty acids for cardiovascular prevention
16:10 - 16:35 - Magnus Bäck* -
Karolinska Institutet & University Hospital, Stockholm, Sweden; INSERM U1116, Nancy, France
Resolving cardiovascular inflammation through omega-3-derived lipid mediators
16:35– 17:14 Selected speakers (3x13 min incl Q&A)
16:35 – 16:48 Sven-Christian Pawelzik - Karolinska University Hospital Solna, Sweden
Prostacyclin is an endogenous protection against aortic stenosis progression and aortic valve prosthesis deterioration
16:48 – 17:01 Frances Yen - INSERM U1116, University of Lorraine, France
Increased lipid dyshomeostasis in metabolic syndrome due to deletion of resolvin D2 receptor GPR18 in mice
17:01 – 17:14 Nathalie Mercier - Université de Lorraine, Inserm U1116, France
Deletion of GPR18 in mice leads to altered vascular mechanical properties
17:15 - Prize Winners and travel support announcements (Young session awards, Poster Prizes,etc)
17.30 - Adjourn: Workshop closing address by Xavier Norel & host for 11th EWLM |
