© 2009-2010 European
Workshop on Lipid Mediators

Supported by:

Book abstract Committees and Contact IV European Workshop on Lipid Mediators

Document sans nom



8:30-10:00 Registration, coffee and poster set-up

10:00-10:05 Welcome by the Organizers

Opening lecture

10:05-10:45 Charles N. Serhan (Brigham & Women’s Hospital, HMS, Boston, MA, USA)
Resolution of inflammation; A novel genus of anti-inflammatory and pro-resolving lipid mediators.

* indicates selected speakers from the abstracts

Session 1. The Pharmacology of Lipid Mediators

 Part 1: "Targets and Bullets in cardiovascular and respiratory diseases"

Chairpersons : Joan Clària, Hospital Clínic-IDIBAPS, Barcelona & Xavier Norel, INSERM, Paris

10:45-11:10 Jane A. Mitchell (Imperial College, London, UK)
Prostanoids in respiratory and vascular inflammation.

11:10 -11:35 Ingrid Fleming (Goethe University, Frankfurt, Germany )
Epoxyeicosatrienoic acids & vascular function.

11:35-11:55 Ignacio Garcia-Verdugo* (Pasteur Institute, Paris, France)
A role for 12R-lipoxygenase in mucus production by respiratory epithelial cells.

11:55-12:15 Gokce Topal* (Istanbul University, Turkey)
Involvement of prostaglandin F2alpha in preeclamptic human umbilical vein vasospasm: a role of FP and TP receptors.

12:15-12:35 Angelo Sala* (University Of Milan, Italy)
Transcellular biosynthesis of leukotrienes in vivo.

 12:35-14:35 Lunch



Part 2: "Targets and Bullets in inflammation, cancer, musculoskeletal and neuronal diseases"

Chairperson : Francis Berenbaum, CNRS, Paris & Joan Clària, Hospital Clínic-IDIBAPS, Barcelona

 14:35-15:00 Sylvain Doré (Johns Hopkins University, Baltimore, USA)
Prostaglandins receptors in Stroke.

15:00-15:25 Oliver Werz (University of Frankfurt, Tübingen, Germany)
5-Lipoxygenase in health and disease.

15:25-15:50 Leslie J. Crofford (University of Kentucky, Lexington, USA)
mPGES-1 as a novel target for inflammation in musculoskeletal diseases.

15:50-16:10 Marjolaine Gosset* (Paris VI University, France)
I nhibition of MMP-3 and MMP-13 synthesis induced by IL-1beta; in chondrocytes from mice lacking microsomal prostaglandin E synthase-1.

16:10-16:30 Saul Yedgar* (Hebrew University - Hadassah Medical School, Israel)
Inclusive control of lipid mediator production: a multi-factorial approach to treatment of inflammatory/allergic diseases.

16:30-17:00 Coffee Break : Poster session and Exhibition visit

Session 2. Non-mammalian Lipid Mediators

Chairperson : Gerard Bannenberg , CSIC, Madrid & Francis Berenbaum, CNRS, Paris

17:00-17:25 Ernst Oliw (Uppsala University, Uppsala, Sweden)
Fungal fatty acid dioxygenases.

17:25-17:50 Ivo Feussner (Georg-August University, Göttingen, Germany)
Oxylipins & host-pathogen interactions in plants.

17:50-18:10 Bodil Björndal* (Institute of Medicine, University of Bergen, Norway)
Krill and fish oil: differences in composition and anti-inflammatory properties.

18:10-18:30 Ivan Chechetkin* (Kazan Institute of Biochemistry and Biophysics, Russia)
Linolipin biosynthesis as a new kind of plant defense strategy.

18:30-18:50 Maite Sanmartin* (Centro Nacional de Biotecnología CSIC, Madrid, Spain )
Increasing omega-3 desaturase expression in tomato results in altered aroma profile and enhanced resistance to cold stress.

 Closing Remarks for Day 1 Gerard Bannenberg, CSIC, Madrid

 Cheese and Wine Session




9:00-9:05 Morning address by organizers

Francis Berenbaum, CNRS, Paris

Session 3. Young Investigator Session (detailed program)

Chairperson: Charles Brink & Xavier Norel & Lhousseine Touqui, INSERM - Pasteur Institute, Paris

 9:05-10:50 8 junior speakers, 8+4 min. to be selected from abstract submissions

 10:50-11:20 Coffee Break : Poster session and Exhibition visit

 11:20-12:30 7 junior speakers, 8+4 min. to be selected from abstract submissions

12:30-14:15 Lunch

 Session 4. Lipid Mediators in Innate Immunity

Chairperson : Lhousseine Touqui, Pasteur Institute, Paris & Lisardo Boscá, CSIC, Madrid

14:15-14:40 María A. Balboa (Spanish Research Council, Valladolid, Spain)
Innate immune signaling & phospholipases.

14:40-15:05 Jesper Z. Haeggström (Karolinska Institut, Stockholm, Sweden)
Leukotrienes & innate immunity.

15:05-15:30 Martin Thurnher (University of Innsbrück, Austria)
Dendritic cells and innate immunity.

15:30-15:50 Janos Filep* (University of Montreal, Canada)
Aspirin-triggered lipoxins facilitate resolution of inflammation by promoting neutrophil apoptosis.

15:50-16:10 Jonas Bystrom* (William Harvey Research Institute, London, UK)
Epoxygenases in control of macrophage phenotype.

16:10-16:30 Pierre Borgeat* (Centre de recherche du CHUQ,(CHUL), Quebec, Canada)
The extra domain A of fibronectin primes leukotriene biosynthesis through Toll- like receptor-4 and stimulates human neutrophil migration.

 16:30-17:00 Coffee Break : Poster session and Exhibition visit

 Session 5. Lipidomics

Chairperson : Jesús Balsinde, CSIC, Valladolid & Gerard Bannenberg , CSIC, Madrid

 17:00-17:25 Anthony Postle (University of Southampton, UK)
The specificty of hepatic phosphatidylcholine synthesis in vivo by the CRP: Choline and PEMT pathways.

17:25-17:50 Michel Lagarde (INSERM, Lyon, France)
Poxotrins; a new family of bioactive triene derivatives.

17:50-18:15 Michel Record* (INSERM U563, Toulouse, France)
The bioactive exosome vesicles involved in the immune response are transcellular vectors of lipolytic enzymes and prostaglandins.

18:15-18:40 GerardLambeau (CNRS UMR 6097, Université Nice-Sophia Antipolis, France)
Emerging and diverse roles of secreted phospholipases A2 in physiology and pathophysiology: a particular focus on the group X enzyme.

Workshop closing address by organizers